平衡脉动整体人工心脏的腹腔输出
Oskar J Gülcher1,2, Annemijn Vis1, Mathias Peirlinck2
1Department of Cardiothoracic Surgery, Amsterdam University Medical Centers, Location University of Amsterdam, Amsterdam, The Netherlands.
Artificial organs
|September 13, 2023
概括
在全人工心脏 (TAH) 中实现平衡心脏输出需要特定的策略. 单独启动的气动TAH为血液动力学适应提供了简单有效的解决方案.
科学领域:
- 生物医学工程 生物医学工程
- 心血管器械 心血管器械
- 人工器官的人工器官
背景情况:
- 在全人工心脏 (TAH) 中平衡左室和右室输出对于血液动力学稳定性至关重要.
- TAH需要不断适应不断变化的生理条件.
- 右心室体积效率对于输出平衡来说是一个独特的挑战.
研究的目的:
- 审查在脉动性TAH中平衡左室和右室输出的方法.
- 根据它们的执行机制对这些方法进行分类.
- 确定TAH输出调节的最有效策略.
主要方法:
- 对TAH输出平衡策略的现有文献的审查.
- 按操作机制 (例如气动,液压) 分类方法.
- 分析技术,包括符合标准的材料,气,主动控制和变速器.
主要成果:
- 策略包括符合标准的材料,气,主动填充控制和变速器.
- 减少右心室中风体积有助于输出平衡.
- 在脉冲式TAH中单独控制的激活可提高预加载灵敏度和输出平衡.
- 气动驱动的TAH表现出对预装载变化的被动反应.
结论:
- 一个带有单独启动心室的气动TAH是一种有前途的方法.
- 这种设计在响应血液动力学变化时提供了简单性和有效性.
- 单独启动的气动TAH为TAH应用提供了理想的解决方案.
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