全球观点:撒哈拉以南非洲前列腺癌的最新情况
Mohamed Jalloh1,2, Ayun Cassell3, Lamine Niang1
1Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.
BJU international
|September 13, 2023
概括
前列腺癌 (PCa) 在撒哈拉以南非洲 (SSA) 构成重大威胁,原因是查和诊断机会有限. 需要创新策略来改善早期检测和治疗,以获得更好的结果.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 全球健康 全球健康
背景情况:
- 前列腺癌 (PCa) 在撒哈拉以南非洲 (SSA) 是一个严重的健康挑战,其特点是高发病率和死亡率.
- 前列腺特异性抗原 (PSA) 查的有限可用性和负担能力阻碍了SSA的早期检测工作.
- 在SSA,诊断和治疗资源稀缺,导致晚期诊断和更差的预后.
研究的目的:
- 在撒哈拉以南非洲探索前列腺癌的替代性和成本有效的查策略.
- 确定挑战和潜在的解决方案,以改善前列腺癌诊断和治疗在SSA.
- 突出意识的重要性,政策变化和了解前列腺癌控制的遗传因素在SSA.
主要方法:
- 审查目前的前列腺癌查,诊断和治疗实践在撒哈拉以南非洲.
- 分析该地区获得前列腺癌医疗保健服务的障碍.
- 探索潜在的策略,包括风险分层,成本有效的PSA测试和改善医疗保健基础设施.
主要成果:
- 前列腺特异性抗原 (PSA) 查在SSA中并不广泛可获得或负担得起.
- 由于对MRI和活检等诊断工具的获取有限,诊断往往会延迟.
- 治疗选择经常受到资源限制和训练有素的医疗保健专业人员短缺的限制.
结论:
- 在SSA中,急需可访问和负担得起的前列腺癌查和诊断工具.
- 提高患者和社区意识,以及政策宣传,对于改善前列腺癌护理至关重要.
- 了解遗传因素和实施全面的,资源敏感的策略可以改善前列腺癌在SSA的结果.
相关概念视频
Disorders of the Male Reproductive System
453
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
453
mTOR Signaling and Cancer Progression
3.8K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
The mTOR pathway or the...
3.8K
Cancer Survival Analysis
381
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
381
Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K


