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聚合物微粒装载in situ凝与普雷迪尼索隆酸用于眼部炎症:开发和评估

Nikita Kaushal1, Manish Kumar2, Abhishek Tiwari3

  • 1M. M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, 133207, Haryana.

Nanomedicine (London, England)
|September 13, 2023
PubMed
概括

一种新的普得尼索隆酸聚合米塞尔 (PM) 系统有效治疗过敏性脑膜炎. 这种配方显示了增强的眼部药物输送,可能是一个有前途的局部治疗前膜炎.

关键词:
捕获效率 捕获效率 捕获效率眼科多聚合物微粒.通过角膜穿透.紫外线炎 (uvéitis) 是一种

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相关概念视频

Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...