在乳腺扩散幻影中,跨3T扫描仪的多站点MRI内素不连贯运动可重复性和可复制性:一个乳腺内素不连贯运动多站点 (BRIMM) 研究研究
Dibash Basukala1,2, Artem Mikheev1, Varadan Sevilimedu3
1Department of Radiology, Center for Advanced Imaging and Innovation (CAI2R), Center for Biomedical Imaging, NYU Langone Health, New York City, New York, USA.
Journal of magnetic resonance imaging : JMRI
|September 13, 2023
概括
扩散加权成像,包括明显扩散系数 (ADC) 和内不连贯运动 (IVIM) 分析,在不同MRI扫描仪和部位中显示出乳腺瘤特征的有希望的可重复性和可重复性.
科学领域:
- 医疗成像医学成像
- 放射学 放射学是一门学科.
- 生物物理学的生物物理.
背景情况:
- 使用显微扩散系数 (ADC) 和内不连贯运动 (IVIM) 分析的扩散加权成像 (DWI) 有助于乳腺瘤的特征.
- 关于这些MRI技术在不同扫描仪和机构的可重复性和可重复性的研究有限.
研究的目的:
- 评估乳腺扩散幻影的ADC和IVIM参数 (组织扩散率 (Dt), perfusion 分数 (Fp) 和伪扩散 (Dp)) 的可重复性和可重复性.
- 在不同MRI扫描仪供应商和多个机构中评估这些参数.
主要方法:
- 使用了一个乳房幻影,其中含有不同度的聚烯酸乙 (PVP),水,脂肪和海绵流体室.
- 双极梯度两次重定焦旋回声和单极梯度单旋旋回声序列在3T时被应用.
- 研究在两个不同的地点和天重复,ADC值正常化为供应商校准的值.
主要成果:
- ADC和Dt表现出优异的内部和跨站点重复性和可重复性 (<5%).
- Fp和DP表现出良好的重复性,但适度的可重复性,Fp的位置间变化很大.
- Fp和Dt与流速有很好的相关性,Fp相关性具有统计学意义.
结论:
- IVIM参数,特别是Dt,显示出有希望的可复制性,可与乳房MRI中的ADC相比.
- 虽然现场内结果始终是可复制的,但现场间的可复制性有所不同,特别是在FP.
- 可能需要进一步标准化,以提高IVIM参数的站点间可重复性.
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