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Updated: Jul 16, 2025

Temporal Analysis of the Nuclear-to-cytoplasmic Translocation of a Herpes Simplex Virus 1 Protein by Immunofluorescent Confocal Microscopy
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Temporal Analysis of the Nuclear-to-cytoplasmic Translocation of a Herpes Simplex Virus 1 Protein by Immunofluorescent Confocal Microscopy

Published on: November 4, 2018

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一个基于CRISPR的快速DNA重新定位策略和HSV-1的早期核内生命

Juan Xiang1, Chaoyang Fan1, Hongchang Dong1

  • 1The Centre for Infection and Immunity Studies, School of Medicine, Shenzhen Campus of Sun Yat-sen Univeristy, Sun Yat-sen University, Shenzhen, China.

eLife
|September 13, 2023
PubMed
概括

一个基于CRISPR的新工具,CRISPR-nuPin,可以快速将病毒DNA重置到核外围. 这种操纵揭示了简单疹病毒1 (HSV-1) 的早期核外围定位抑制了病毒基因表达和生长.

关键词:
在CRISPR/dcas9中使用.病毒DNA病毒DNA病毒在HSV-1病毒中,细胞生物学 细胞生物学异性染色素包装的包装人类 人类 人类 人类 人类 人类 人类传染病是一种传染性疾病.内核定位是指核内部的定位.微生物学的微生物.病毒病毒病毒病毒.

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