在患有III级,IV级或V级膀肠道逆流症的婴儿中进行抗生素预防

William Morello1, Esra Baskin1, Augustina Jankauskiene1

  • 1From the Pediatric Nephrology, Dialysis, and Transplant Unit (W.M., G.P., J.S., G.M.) and the Pediatric Urology Unit (D.G.M.), Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, and the Department of Clinical Sciences and Community Health, University of Milan (G.M.), Milan, the Department of General and Specialized Surgery for Women and Children, Università degli Studi della Campania "Luigi Vanvitelli," Naples (A.L.M., S.G., P.M.), the Institute for Maternal and Child Health-IRCCS Burlo Garofolo (M.P., E. Barbi) and the Department of Medical, Surgical, and Health Sciences, University of Trieste (E. Barbi), Trieste, Pediatric Nephrology and Dialysis, Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna (C.L.S., A.P.), the Nephrology and Dialysis Unit, Meyer Children's Hospital, Florence (F.B., M.M.), Pediatria C, Ospedale Donna Bambino, Verona (M.B.), the Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria Gaetano Martino, University of Messina, Messina (R.C.), the Nuclear Medicine Unit, Circolo Hospital and Macchi Foundation, Azienda Socio Sanitaria Territoriale Sette Laghi, Varese (D.D.P.), the Nuclear Medicine Unit, Department of Medicine, University Hospital of Padua (P.Z.), and the Pediatric Nephrology, Dialysis, and Transplantation Unit, Department of Women's and Children's Health, University of Padua (I.A.), Padua - all in Italy; the Department of Pediatric Nephrology, Başkent University Faculty of Medicine (E. Baskin, K.G.), and the Department of Pediatric Nephrology, Ankara University School of Medicine (F.Y., Z.B.O.), Ankara, the Department of Pediatric Nephrology and Pediatric Rheumatology, Pamukkale University School of Medicine, Denizli (S.Y.), and the Department of Pediatric Nephrology, Istanbul University-Cerrahpaşa, Cerrahpaşa School of Medicine, Istanbul (S.C.) - all in Turkey; the Pediatric Center, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius (A.J., D.R.), and the Department of Radiology, Medical Academy, Lithuanian University of Health Sciences Kauno Klinikos, Kaunas (D.V.) - both in Lithuania; the Department of Pediatrics, Nephrology, and Hypertension, Medical University of Gdansk, Gdansk (A.Z., A.K.), the Department of Pediatrics and Nephrology, Medical University of Warsaw, Warsaw (G.K., A.S.), the Department of Pediatric Nephrology and Hypertension, Chair of Pediatrics, Pediatric Institute, Jagiellonian University Medical College, Krakow (D.D.), the Department of Pediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Katowice (M.S.), the Department of Pediatrics and Nephrology, Medical University of Bialystok, Bialystok (K.T.-J.), and the Department of Pediatrics, Immunology, and Nephrology, Polish Mother's Memorial Hospital Research Institute, Lodz (M.T.) - all in Poland; the Department of Pediatric Nephrology, University Hospitals Leuven (D.M., S.D.R.), and PKD Research Group, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven (D.M.), Leuven, and the Division of Nephrology, Department of Pediatrics, University Hospital Center of Liège, Liège (J.L.) - all in Belgium; the Department of Pediatric Nephrology, University Hospital Vall d'Hebron, and Universidad Autónoma de Barcelona, Hospital Vall d'Hebron (G.A.), and Pediatric Nephrology, Hospital General de Granollers, Universitat Internacional de Catalunya (M.C.), Barcelona, and Hospital General Universitario Santa Lucía, Cartagena (J.E.C.S.) - all in Spain; the University of Cologne, Faculty of Medicine and University Hospital Cologne, Children's and Adolescents' Hospital, Cologne (L.T.W.), and the Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg University Hospital, Heidelberg (O.M., F.S.) - both in Germany; and the Division of Pediatric Nephrology, Centro Materno Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto, Portugal (A.C.A.).

PubMed
概括

持续的抗生素预防可显著降低患有严重膀回流的婴儿的第一个尿路感染 (UTI). 然而,它也增加了抗生素耐药性和非大肠杆菌感染.

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