益生菌用于预防重症和创伤患者的感染:简要的综述
Heather A Vitko1, Jordan J Troxell, Paula R Sherwood
1Department of Acute and Tertiary Care, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania (Drs Vitko and Sherwood); UPMC Pinnacle, Harrisburg, Pennsylvania (Mr Troxell); and Lung Innovations Network, P.C., State College, Pennsylvania (Mr Troxell).
概括
对重症创伤患者的益生菌补充剂显示出预防感染的前景,但证据仍然混杂. 大多数研究表明有好处,尽管关于感染率和患者结果的进一步研究正在等待最终结论.
科学领域:
- 关键护理医学 关键护理医学
- 预防传染病 预防传染病
- 微生物组研究的研究.
背景情况:
- 重症创伤患者面临高感染风险,增加发病率和死亡率.
- 在这种人群中,使用益生菌预防感染是一种有前途的策略.
- 关于益生菌有效性的现有研究产生了不同的结果.
研究的目的:
- 综合当前关于益生菌的研究,用于预防和治疗严重疾病的成年创伤患者的感染.
- 评估益生菌在降低感染率和改善治疗结果方面的有效性.
- 为临床决策提供基于证据的概述.
主要方法:
- 对现有文献进行系统审查.
- 对调查创伤患者益生菌干预的研究进行分析.
- 报告的感染率和患者结果的评估.
主要成果:
- 在重症创伤患者中补充益生菌的证据尚未确定.
- 大多数公布的数据表明益生菌的潜在益处.
- 需要进一步的研究才能确定有效性.
结论:
- 目前的证据并不能最终证实在重症创伤患者中益生菌降低了与医疗保健相关的感染率.
- 然而,大多数发表的证据都支持益生菌的使用.
- 需要进一步的研究来巩固益生菌在这个患者群体中的作用.
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