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关氨酸核酸交换因子Rin-like通过CD28信号控制Tfh细胞分化

Lisa Sandner1, Marlis Alteneder1, Ramona Rica1

  • 1Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

The Journal of experimental medicine
|September 13, 2023
PubMed
概括

关氨酸核酸交换因子 (GEF) 类似Rin的 (Rinl) 负面调节T毛囊辅助细胞 (Tfh) 的生成. 失去Rinl会增加Tfh细胞,通过CD28信号传递影响T细胞的激活和分化.

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