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像Chilblain这样的喷发揭示了急性髓性白血病的皮肤白血病复发
Cláudia Brazão1, Dora Mancha1, Sofia Antunes-Duarte1
1Dermatology and Venereology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal.
The American Journal of dermatopathology
|September 13, 2023
概括
皮肤白血病,急性髓性白血病 (AML) 的皮肤表现,可以呈现为不寻常的状病变. 早期的组织病理学诊断对于识别AML病史患者的白血病复发至关重要.
科学领域:
- 血液学 血液学 血液学
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 皮肤白血病 (Leukemia cutis) 涉及恶性造血细胞透到皮肤,通常在急性髓性白血病 (AML) 中见到,特别是在单细胞参与的情况下.
- 皮肤白血病的临床表现是高度可变的,使皮肤白血病透的组织病理学诊断具有挑战性.
- 在老年人中,原发性寒是罕见的,需要对潜在的系统性原因进行调查.
研究的目的:
- 报告第一例AML皮肤性白血病复发病例,呈现为不寻常的状喷发.
- 为了突出这一罕见的白血病病例所带来的诊断挑战.
- 强调非典型寒冷症患者的病学检查的重要性,特别是在有血液学疾病病史的患者中.
主要方法:
- 一个有AML病史的患者的病例报告.
- 临床和组织病理学检查非典型的,持久的,类似于寒的皮肤病变.
- 关于皮肤白血病和寒状喷发的文献综述.
主要成果:
- 患者呈现出一种不寻常的寒状的喷发,代表AML的异构,白血病复发.
- 呈现模仿了初级寒冷,但是持久的,耐治疗的.
- 组织病理学检查证实白血病透,需要及时治疗.
结论:
- 皮肤,AML的白血病复发可以表现为非典型的状病变.
- 组织病理学评估对于在患有血液学疾病和不寻常的皮肤发现的患者中诊断白血病关键.
- 早期诊断和治疗对于治疗复发性白血病至关重要,即使是在白血病阶段.
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