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含有精选剂的化学病毒:它们的产生,减弱和排除监管背后的生物学

Elizabeth W Wells¹, Michael T Parker²

¹Elizabeth W. Wells is a Student, Department of Biology, Georgetown College of Arts & Sciences, Georgetown University, Washington, DC.

Health security

|September 13, 2023

概括

美国疾病控制和预防中心 (CDC) 以前排除了许多仿真病毒. 最近将一种仿真病毒添加到精选剂清单中,与既定的监管实践背道而.

科学领域:

病毒学病毒学
公共卫生政策公共卫生政策
监管科学监管科学

背景情况:

美国疾病控制和预防中心 (CDC) 监管特定的毒素和毒素,包括某些仿真病毒.
从历史上看,疾病预防控制中心已经排除了20多种含有精选代理成分的仿真病毒,因为自2003年以来的足够衰减.
在2021年底,疾病预防控制中心 (CDC) 提议将仿真病毒添加到精选剂清单中,这与之前的监管行动有所不同.

研究的目的:

分析过去从精选剂监管中排除的仿真病毒.
了解疾病预防控制中心在调控仿真病毒时使用的标准和模式.
评估与历史监管实践相比,最近增加的SARS-CoV-1/SARS-CoV-2仿真病毒.

主要方法:

审查了政府内部选择代理人和毒素技术咨询委员会使用的排除标准.
分析了以前被排除在外的仿真病毒的文献,重点是α病毒和禽流感病毒.
检查了被排除在外的仿真病毒的发展中的生物学共同点和方法.

主要成果:

在以前被排除的仿真病毒中确定了模式和生物学共同点.
展示了疾病预防控制中心 (CDC) 如何在历史上对仿真病毒应用排除标准.
强调最近增加的SARS-CoV-1/SARS-CoV-2仿真病毒与已建立的监管流程有所不同.

结论:

疾病预防控制中心最近将SARS-CoV-1/SARS-CoV-2仿真病毒添加到精选剂清单中,代表了与历史监管实践的偏离.
这一行动似乎是一个监管错误,不与管理仿真病毒的既定和有效流程保持一致.
对过去排斥的分析为评估有关转基因病原体的当前监管决策提供了背景.

关键词:

基梅里克病毒基梅里克病毒双重使用科学科学规则规则规则规则规则规则这就是SARS-CoV.选择代理人选择代理人

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