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研究扫描路径优化在改善质子笔束扫描连续交付的优化

Chunbo Liu¹, Chris J Beltran², Jiajian Shen³

¹Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.

Physics in medicine and biology

|September 13, 2023

概括

扫描路径优化提高了质子疗法中剂量准确度.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学

背景情况:

质子笔束扫描 (PBS) 是一种精确的放射治疗技术.
剂量驱动连续扫描 (DDCS) 是PBS的先进输送模式.
扫描路径优化对于提高治疗交付效率和准确性至关重要.

研究的目的:

评估扫描时间和扫描长度优化对DDCS质子疗法中剂量准确性和光束传递时间 (BDT) 的影响.
将优化的扫描路径与默认的蛇形扫描路径进行比较.

主要方法:

分析了六个不同的临床质子疗法计划.
应用了扫描时间优化和扫描长度优化策略.
剂量差异 (使用马分析) 和BDT与默认扫描路径进行了比较.

主要成果:

与默认扫描路径相比,这两种优化方法都显著减少了剂量差异.
大多数计划实现了>99%的马通过率和<1%的PTV DVH RMSE优化.
层重绘肺部图表显示了玛传导率和PTV DVH RMSE的显著改善.
扫描路径优化对总BDT的影响最小.

结论:

扫描时间和扫描长度的优化有效地将DDCS质子治疗中的剂量差异降到最低.
两种优化方法都没有在剂量准确性方面显示出明显的优势.
扫描路径优化对整体光束传递时间的影响微不足道.

关键词:

剂量驱动的连续扫描.质子 PBS 质子 PBS 的时间扫描路径优化扫描路径优化

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