伴侣关系质量和IL-6:IL-10轨迹从怀孕到出生后的一年
Alexandria Lozowchuk1, Judith E Carroll2, Calvin Hobel3
1Psychology Department, University of Calgary, Calgary, AB, Canada.
Brain, behavior, and immunity
|September 13, 2023
概括
怀孕期间的下部伴侣支持与改变的炎症标志物 (IL-6:IL-10) 产后有关. 这表明对产后母亲健康和康复的潜在影响.
科学领域:
- 生殖免疫学和孕产妇健康研究.
- 心理神经免疫学和与压力相关的健康结果.
背景情况:
- 怀孕和产后涉及炎症活动的显著转变.
- 破坏炎症平衡的因素可能会对怀孕结果和恢复产生负面影响.
- IL-6:IL-10和TNF-α:IL-10比率可能表明外周炎症调节的有效性.
研究的目的:
- 调查伴侣关系质量 (支持和冲突) 与炎症标志物轨迹 (IL-6,IL-10,TNF-α及其比例) 之间的关联,从怀孕晚期到产后期.
主要方法:
- 162名妇女通过血液样本提供了有关伴侣关系质量和炎症标志物 (IL-6,IL-10,TNF-α) 的数据.
- 测量是在妊娠的第三个三个月,以及分娩后的1,6个月和12个月.
- 使用多级建模来分析关系质量与炎症标志物轨迹之间的关系,控制共变量.
主要成果:
- 较低的伴侣支持与随着时间的推移IL-6:IL-10比率的显著变化有关,这表明抗炎控制降低.
- 具体来说,较低的支预测了从怀孕晚期到产后一年的IL-6:IL-10的急剧增加和随后的减少.
- 伴侣冲突和个体炎症标志物 (IL-6,IL-10,TNF-α) 或TNF-α:IL-10比率与关系质量指标没有显著关联.
结论:
- 减少伴侣支持可能与从怀孕到产后一年的关键时期IL-6的IL-10适度降低有关.
- 这些与较低的伴侣支持相关的炎症失调可能会对母亲的健康和福祉产生影响.
更多相关视频
相关概念视频
Development of Immunocompetence
342
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
342
Relationship Formation
40.1K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
40.1K
Theory of Romantic Attachment in Adulthood
43.5K
Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships.
43.5K
Socioemotional Development during Infancy
84
Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
Primary Temperament Types
84
Parental Care
11.8K
Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
11.8K
Transcytosis of IgG
2.8K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.8K


