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Updated: Jul 16, 2025

Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis
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Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis

Published on: June 17, 2019

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马类疹病毒重组的全面分析:对重复区域的洞察

Rocío Lucía Tau1, Carola Ferreccio2, Natalia Bachir1

  • 1Institute of Virology and Technological Innovations, IVIT (INTA-CONICET), Dr Nicolas Repetto and De los Reseros, CP 1686, Hurlingham, Buenos Aires, Argentina.

Journal of equine veterinary science
|September 13, 2023
PubMed
概括

马类疹病毒重组,增加遗传多样性. 这项研究确定了所有马类阿尔法疹病毒物种的新型重组事件,突出了感染细胞蛋白4 (ICP4) 作为重组热点.

关键词:
阿尔法赫尔佩斯病毒 (alphaherpesvirus) 是一种马匹的疹病毒同类的重组组合.感染细胞蛋白 4 感染细胞蛋白

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Author Spotlight: Characterizing DNA Replication of Pathogenic Repeats to Uncover Mechanisms of Replication Fork Stalling and Expansion05:22

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Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Conservative Site-specific Recombination and Phase Variation

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Homologous Recombination

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Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
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