相关实验视频

Updated: Jul 16, 2025

Rapid Generation of Amyloid from Native Proteins In vitro
05:48

Rapid Generation of Amyloid from Native Proteins In vitro

Published on: December 5, 2013

6.2K

对于N/C终端受保护的amyloidogenic的模块化合成策略

Taka Sawazaki1, Youhei Sohma1

  • 1Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.

Journal of peptide science : an official publication of the European Peptide Society
|September 13, 2023
PubMed
概括

合成具有多种N / C-终端保护的amyloidogenic是一种挑战. 这项研究引入了使用前体序列的模块化液相策略,使各种受保护的氨基类的高效合成成为可能.

关键词:
氨基化物 氨基化物凝凝是一种凝.模块化合成 模块化合成这是一种类.

更多相关视频

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

7.3K
Constructing Cyclic Peptides Using an On-Tether Sulfonium Center07:11

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

Published on: September 28, 2022

2.7K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.6K