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在查结肠镜检查中检测高风险的息肉表明肝癌和胆道癌死亡风险

Jasmin Zessner-Spitzenberg¹, Arnulf Ferlitsch², Elisabeth Waldmann¹

¹Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria; Quality Assurance Working Group, Austrian Society of Gastroenterology and Hepatology, Vienna, Austria.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

|September 13, 2023

概括

患有高风险结肠多的患者面临双倍的死于肝癌的风险. 这突显了结直肠癌查结果与肝胆癌死亡率之间的潜在联系.

科学领域:

胃肠病学胃肠病学
肝病学肝病学是一种肝病学.
在瘤学瘤学.

背景情况:

肝胆道癌和结直肠癌 (CRC) 具有共同的风险因素.
目前的查计划没有整合CRC和肝胆癌的检测.

研究的目的:

为了确定患有高风险结肠多的患者与阴性结肠镜检查患者相比,患有肝脏相关瘤的死亡率是否更高.
调查高风险息肉与肝胆癌死亡之间的关联.

主要方法:

来自奥地利查参与者的死亡率数据 (2007-2020年) 的回顾性分析.
使用累积发病率计算肝胆癌死亡的绝对风险.
雇佣了Cox的比例危险模型来评估与死亡时间的关联.

主要成果:

分析包括343,838次结肠镜检查;5.14%的检查显示高风险的息肉.
肝胆癌的死亡率在患有高风险息肉的患者中高出两倍 (0.39%) 与阴性结肠镜 (0.17%) 相比.
在调整年龄和性别后,高风险的息肉与肝胆癌死亡有显著的关联 (HR1.83,p < 0.001).

结论:

某些结肠多的特征表明肝脏恶性瘤死亡率的风险较高.
需要进一步的研究来探索这种患者群体中额外查肝病的好处.

关键词:

结肠镜检查是一次结肠镜检查.肝脏的新生体是什么查检查查检查查检查

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