低收入和中等收入国家的儿童浪费和并发性衰老
Andrew Mertens1, Jade Benjamin-Chung2,3,4, John M Colford2
1Division of Epidemiology and Biostatistics, University of California, Berkeley, Berkeley, CA, USA. amertens@berkeley.edu.
Nature
|September 13, 2023
概括
儿童消耗是动态的, 许多儿童经历的事件比以前想象的. 从出生到六个月的早期干预对于预防和降低死亡风险至关重要.
科学领域:
- 全球健康
- 儿童医学
- 营养科学
背景情况:
- 儿童浪费是一个关键的全球健康问题,目标是到2030年消除.
- 目前的测量方法 (横截面调查) 无法捕捉浪费的动态性质,包括开始,恢复和持久性.
- 了解这些动态对于有效的干预和准确的疾病负担估计至关重要.
研究的目的:
- 分析纵向数据以了解儿童消耗的动态.
- 确定浪费开始和恢复的关键时期.
- 为消除营养不良提供有针对性的干预.
主要方法:
- 对21个儿童成长数据的纵向队列的分析.
- 在生命的前24个月中检查体重与长度的z-score.
- 评估浪费的发生率,恢复,持久性以及相关的风险因素.
主要成果:
- 流产是一个动态的过程,发病率在出生到3个月之间达到顶峰.
- 显著比例的儿童 (29.2%在24个月) 经历至少一次消耗事件,远远超过点患病率.
- 早期消耗 (在6个月之前) 与更快的恢复有关,但增加了以后生长失速,衰老和死亡的风险.
- 重量对长度z分数的季节性变化与降雨相关,这表明季节性干预的可能性.
结论:
- 预防从出生到6个月的浪费,可能通过母体营养,是必不可少的.
- 目前专注于6-59个月龄的儿童的计划应补充早期生活策略.
- 解决季节性浪费问题可能会提高相关地区的干预效率.
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