在智力和发育障碍学生的六所学校中发现了SARS-CoV-2感染的集群
Michael Gemmell1, Tyler Walsh2, Michael Sherby3
1Division of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO, 63110, USA. m.gemmell@wustl.edu.
Infectious diseases and therapy
|September 13, 2023
概括
奥米克朗变种在智力和发育障碍者中显著增加了COVID-19学校集群. 保持最新的疫苗接种对于限制2019年冠状病毒疾病的传播至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 智力和发育障碍 (IDD) 患者面临的风险更高,因为2019年新冠肺炎疾病 (COVID-19) 的严重后果.
- 学校是IDD个体的关键环境,因此对于监测SARS-CoV-2传播至关重要.
- 在学校跟踪COVID-19集群有助于了解这个脆弱人群中的传播动态.
研究的目的:
- 为了比较学生和工作人员COVID-19集群的发病率在三个大流行阶段:前Delta,Delta和Omicron变种.
- 分析不同SARS-CoV-2变种对学校传播的影响.
- 评估疫苗接种状态在教育环境中对IDD患者的COVID-19传播中的作用.
主要方法:
- 从2020年11月到2022年5月进行的每周COVID-19测试.
- 与阳性病例进行结构化采访,以确定与学校有关的感染.
- 与学校管理人员的采访,以确认学校的COVID-19集群.
主要成果:
- 总共有160个COVID-19病例和55个集群阳性病例被确定.
- 在Delta前没有发现集群;在Delta期间3% (3/55);在Omicron期间95% (52/55).
- 显著比例的阳性病例,包括在Omicron期间的集群病例,没有接受推的COVID-19疫苗剂量.
结论:
- 奥米克朗变异与学校内COVID-19集群的大幅增加有关.
- 保持最新的疫苗接种状态对于在学校环境中减轻SARS-CoV-2传播至关重要.
- 调查结果强调了在流行病浪潮期间为IDD患者制定有针对性的公共卫生战略的必要性.
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