斑点棕叶角皮肤病1型是否与恶性瘤有关? 一个系统的文献审查
S B Gram1,2, J Bjerrelund3,4, A M Jelsig5
1Department of Clinical Genetics, Odense University Hospital, J.B. Winsløws Vej 4, Indgang 24, 5000, Odense C, Denmark. stine.bjorn.gram@rsyd.dk.
Orphanet journal of rare diseases
|September 13, 2023
概括
这次审查没有发现点性棕植物皮皮肤类型1 (PPPK1) 和恶性瘤之间的确定的关联. 需要进一步进行高质量的研究,以确定PPPK1是否会增加癌症风险.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
背景情况:
- 多年来,人们一直在讨论穿孔棕植物皮皮质类型1 (PPPK1) 和恶性瘤之间的潜在联系.
- 一些人主张在PPPK1患者中进行癌症查,而另一些人则质疑证据的强度.
结论:
- 目前的文献缺乏精心设计的研究,以确定PPPK1与恶性瘤风险增加之间的明确联系.
- 根据现有证据,无法证实PPPK1与恶性瘤之间的关联.
- 鉴于目前的证据,针对PPPK1个体的常规恶性瘤监测是有问题的.
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