在阿片类药物治疗计划中实施兴奋剂使用的应急管理:III型混合疗效阶段曲试验协议
Sara J Becker1, Kira DiClemente-Bosco2, Kelli Scott2
1Center for Dissemination and Implementation Science, Northwestern University Feinberg School of Medicine, 633 N St Clair Street, Chicago, IL, 60611, USA. Sara.Becker@Northwestern.edu.
Implementation science : IS
|September 13, 2023
概括
应急管理 (CM) 对阿片类药物使用障碍有效,但未得到充分利用. 一项新的实施策略,即服务实验室科学 (SSL),旨在增加CM在治疗计划中的使用,改善患者的治疗结果.
科学领域:
- 药物中毒药物 药物中毒药物
- 实施科学 实施科学
- 公共卫生 公共卫生
背景情况:
- 应急管理 (CM) 是针对兴奋剂使用障碍的基于证据的干预措施,在与阿片类药物使用障碍 (MOUD) 药物相结合时非常有效.
- 尽管其已被证明是有效的,但MOUD计划中CM的采用仍然很低,这凸显了成服务中研究到实践的巨大差距.
- 多层次的实施策略对于克服提供商和组织层面的CM采用障碍至关重要.
研究的目的:
- 为了评估多层次实施战略的有效性,科学服务实验室 (SSL) 在促进阿片类药物治疗计划中的CM实施方面进行了评估.
- 评估SSL对实施结果 (初级) 和患者结果 (二级) 的影响.
- 探索影响CM实施的潜在调解者.
主要方法:
- 一个III型混合有效性实施试验,采用10个阿片类药物治疗方案的阶段设计.
- 该SSL战略包括教学培训,绩效反和外部促进,将在四个连续步骤中实施.
- 数据收集包括多次间隔的CM交付和患者结果的非识别电子病历,以及员工对上下文因素的反.
主要成果:
- 这项研究旨在提供关于SSL在增加CM利用中的有效性的可靠数据.
- 分析将确定SSL对关键实施指标和患者水平结果的影响.
- 探索性目标将确定调解CM成功采用的因素.
结论:
- 服务实验室科学 (SSL) 提供了一个有前途的多层次战略,以弥合在阿片类药物治疗中应急管理的研究与实践之间的差距.
- 通过SSL成功实施CM,预计将提高阿片类药物使用障碍治疗方案中患者的治疗结果.
- 这项试验将为优化成医疗保健中基于证据的实践提供关键见解.
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