在保守治疗的急性尾炎中出现尾恶性瘤的风险
Shaima Ramadan1,2,3, Pamela Buchwald4,5, Åsa Olsson4,5
1Colorectal Unit.
概括
急性尾炎的保守治疗在复杂的情况下显示出更高的复发和恶性瘤风险. 与无并发症病例相比,复杂尾炎患者患恶性瘤和复发的可能性显著增加.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 临床医学 临床医学
背景情况:
- 尾切除术是急性尾炎的传统治疗方法.
- 保守的抗生素治疗越来越多地用于不复杂的尾炎.
- 由于恶性瘤和复发风险,复杂的尾炎可能需要间隔尾切除.
研究的目的:
- 评估保守治疗急性尾炎的随访结果.
- 评估复发率和尾恶性瘤风险.
- 在保守管理后确定间隔尾切除术的必要性.
主要方法:
- 对391名急性尾炎保守治疗的患者进行了回顾性研究 (2012-2019).
- 从医疗图表中收集的人口统计,随访,复发和恶性瘤的数据.
- 对无并发性尾炎与复杂尾炎的结果分析.
主要成果:
- 复杂的 (24.3%) 与无并发症 (15.1%) 尾炎的复发风险更高 (p=0.030).
- 在5%的复杂病例中发现了尾恶性瘤,在无并发病例中没有发现 (p=0.002).
- 23%的复杂病例在随访期间进行了尾切除.
结论:
- 复杂的急性尾炎带有明显更高的恶性瘤和复发的风险比不复杂的病例.
- 由于这些风险增加,保守的管理需要仔细跟进.
- 研究结果表明,需要个性化后续策略.
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