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Updated: Jul 16, 2025

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KIAA1429/VIRMA通过m6的A-依赖细胞质HAS2稳定促进乳腺癌的进展

Na Li1, Zhouting Zhu1, Yufei Deng1

  • 1Division of Genetics, Department of Pediatrics, Program in Immunology, Bioinformatics and Systems Biology Program, Institute for Genomic Medicine, La Jolla, CA, USA.

EMBO reports
|September 14, 2023
PubMed
概括

在乳腺癌中,m6A编辑器KIAA1429/VIRMA被上调,通过通过IGF2BP3.3稳定HAS2mRNA,促进瘤生长和低生存率. 针对这一轴可能会提供新的乳腺癌疗法.

关键词:
在HAS2中,它是HAS2.在 IGF2BP3BP3 中.在KIAA1429/VIRMA中使用.乳腺癌 乳腺癌 乳腺癌m6A 是一种RNA修饰.

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