围喉磨损疗法 (EAT) 对巴罗受体反射 (BR) 的影响
1Otolaryngology, Ito ENT Clinic, Funabashi, JPN.
Cureus
|September 14, 2023
概括
围喉磨损疗法 (EAT) 可以通过抑制副交感活动和刺激交感活动来改善自主神经病变. 这种疗法显示出对诸如正静止失调和POTS等疾病的潜力.
科学领域:
- 自主神经系统研究 自主神经系统研究
- 心血管生理学心血管生理学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 围喉磨损疗法 (EAT) 用于慢性围喉炎.
- 自主神经刺激是EAT治疗效果的一个拟议机制.
- 有限的研究存在于EAT对自主神经系统随着时间的推移的影响.
研究的目的:
- 为了研究重复EAT对慢性喉炎患者自主神经系统活动的影响.
- 为了分析心率变化 (HRV) 和baroreceptor反射 (BR) 功能在EAT之后的变化.
- 为了比较EAT后自主功能改善的患者和没有改善的患者之间的自主功能.
主要方法:
- 追溯性研究39名慢性喉炎患者接受EAT.
- 使用HRV分析和主动站立 (AS) 测试来评估自主功能.
- 评估了副交感和交感活动指数,包括AS测试期间的HRV组件和血压变化.
主要成果:
- 在改善组中,EAT显著抑制了副交感活动.
- 在AS测试中,在改善和不变组中都发现了显著的时间依赖波动.
- 与不变组相比,在改善组中观察到对表同情活动抑制和同情活动刺激的趋势.
结论:
- 随着时间的推移,EAT抑制了副交感活动.
- 虽然AS测试没有显示出对巴罗受体反射的直接相互作用效应,但趋势表明,EAT可能会对自主神经病变产生积极影响.
- EAT的治疗效果可能来自于对自主和免疫系统的协同作用,可能有利于像正静性失调和POTS这样的疾病.
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