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在沙特阿拉伯的三级医院中,布鲁塞拉,热性和结核性脊髓炎:一个比较的回顾性队列研究
Hajar AlQahtani1,2,3, Fatimah Alzahrani4, Ghaida Abalkhail3
1Department of Pharmaceutical Care, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Open forum infectious diseases
|September 14, 2023
概括
这项关于脊髓瘤炎的研究发现,虽然乳头感染是最常见的,但发炎性病例显示出明显的炎症标志物. 有效的治疗包括长时间的抗微生物治疗,通常是手术,达到60%以上的治愈率.
科学领域:
- 传染性疾病 传染性疾病
- 整形外科手术 整形外科手术
- 微生物学 微生物学
背景情况:
- 脊髓炎是一种脊髓感染,在西方国家越来越普遍.
- 它涉及椎间盘和相邻的脊椎的炎症.
- 通常报告的结果包括6-12%的死亡率和潜在的神经学缺陷.
研究的目的:
- 为了评估在国王阿卜杜勒阿齐兹医疗城接受治疗的感染性脊髓炎患者.
- 分析患者的人口统计,致病原体和治疗结果.
- 为了确定不同类型的脊髓脊髓炎中临床和实验室发现的差异.
主要方法:
- 进行了一项多中心回顾性队列研究.
- 包括在2017年1月至2021年11月期间被诊断患有传染性脊髓炎的患者.
- 诊断是基于放射学,微生物学和临床发现.
主要成果:
- 该研究包括76名患者,平均年龄为61岁,所有患者都有背部疼痛.
- 状脊髓炎是最常见的类型 (n=52),其次是结核性 (n=13) 和发烧性 (n=11).
- 发烧性脊髓瘤炎显示显著增加了C反应蛋白,红细胞沉积率和白细胞计数.
结论:
- 背部疼痛是传染性脊髓瘤炎的一个关键临床特征.
- 微生物学和组织学研究对于识别致病原体至关重要.
- 结合长期静脉注射抗微生物治疗和手术的治疗,实现了超过60%的治愈率.
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