预装注射器和掩护剂对静脉注射后内内炎的影响
Abigail M Louis1, Amna M Ali1, Sagar B Patel2,3
1McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA.
Journal of vitreoretinal diseases
|September 14, 2023
概括
与玻璃瓶制剂相比,预填注射器在静脉内注射后显著降低了内炎风险. 在这项大规模研究中,全方位掩护没有影响内眼炎的发病率.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜外科手术 视网膜外科手术
- 传染性疾病 传染性疾病
背景情况:
- 视内膜炎是内内注射后的一种严重并发症.
- 抗静脉内皮生长因子 (抗VEGF) 疗法通常通过静脉内注射进行.
- 抗VEGF药物的制备方法可能会影响感染风险.
研究的目的:
- 为了比较玻璃瓶制剂 (GVP) 和预填注射器 (PFS) 之间的内内的抗VEGF治疗.
- 评估掩护方案对内内膜炎发病率在内内注射后的影响.
主要方法:
- 从多中心视网膜实践中对医疗记录的回顾性审查 (2015年1月 - 2021年8月).
- 分析了307349次静脉内注射的情况.
- 主要结局:内的发病率.
主要成果:
- 总共有101例内眼炎病例 (0.033%) 被确定.
- 与玻璃瓶制备剂 (GVP) (0.052%) 相比,预填注射器 (PFS) 与内炎 (0.017%) 的风险明显较低.
- 没有观察到具有或没有通用掩盖的内眼炎发病率的显著差异.
结论:
- 预填注射器 (PFS) 是内内注射的更安全选择,可以降低内炎的风险.
- 在这项研究中,通用掩护协议没有对内甲状腺炎的发病率产生显著影响.
- 需要进一步研究内内注射的最佳无菌技术.
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