在HIV阴性患者中发生了13例肺肺囊病例
Abir Bouhamdi1, Btissame Es-Sabbahi1, Rajae Amiali1
1Pulmonology Department, Hassan II University Hospital, University of Sidi Mohammed Ben Abdellah, Fez, MAR.
Cureus
|September 14, 2023
概括
肺肺囊炎 (PCP) 可能发生在没有艾滋病毒的患者中,出现严重的症状. 早期诊断和用trimethoprim/sulfamethoxazole和皮质类固醇治疗导致了有利的结果.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 肺性肺囊炎 (PCP) 通常与人类免疫缺陷病毒 (HIV) 感染有关.
- 然而,PCP也会影响免疫力低下但没有艾滋病毒的人.
研究的目的:
- 描述PCP在未感染HIV的患者中的临床特征,诊断和治疗结果.
主要方法:
- 回顾13名未感染艾滋病毒的患者的病例系列,诊断出PCP.
- 诊断方法包括诱导液和支气管支气管洗液 (BAL) 液体分析.
- 治疗包括三甲胺/硫甲醇 (TMP/SMX) 和皮质类固醇.
主要成果:
- 在未感染艾滋病毒的患者中发现了13例PCP病例 (平均年龄55岁).
- 常见的症状包括呼吸不良和严重的缺氧;在9例病例中发现了淋巴缺血.
- 所有患者都表现出TMP/SMX和皮质类固醇治疗的良好结果.
结论:
- PCP是艾滋病毒未感染个体的重大机会性感染,特别是那些患有潜在疾病或接受免疫抑制治疗的人.
- 及时诊断和联合治疗对于有利的预后至关重要.
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