在动感错觉期间皮质脊髓刺激能力的变化,由肌震动诱导
Lydiane Lauzier1, Marie-Pier Perron1, Laurence Munger1
1Lab BioNR, Centre intersectoriel en santé durable, Université du Québec à Chicoutimi, Chicoutimi, Quebec, Canada.
Journal of neurophysiology
|September 14, 2023
概括
振动诱导的动感错觉显示皮质脊髓刺激能力的时间依赖性变化. 在幻觉完全被感知之前,兴奋能力的早期下降发生,这表明了复杂的脊髓和皮质机制.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 身体上的感觉 (somatosensation) 是一种感觉.
背景情况:
- 振动诱导的动感错觉是一个众所周知的现象,但它们的潜在神经生理机制仍然不太清楚.
- 研究皮质脊髓刺激性提供了对中枢神经系统对自身感知输入的反应的洞察.
研究的目的:
- 为了检查通过跨磁刺激 (TMS) 测量的皮质脊髓刺激能力是如何在振动 (VIB) 诱导的动感错觉期间调节的.
- 为了确定这些调节效应的时间动态.
主要方法:
- 20名健康成年人接受了手腕 flexor 肌肉振动 (80 Hz,1 mm,10 秒).
- 跨磁刺激 (TMS) 应用于四个时间点的手腕延伸器的初级运动皮质表示:基线,以及VIB发作后的1,5和10秒.
- 分析了发动机唤起潜能 (MEP) 的幅度和延迟.
主要成果:
- 观察到刺激时间对MEP幅度有显著的影响 (P = 0.035).
- 皮质脊髓刺激性在VIB发作后1秒显著降低,相比5秒和10秒 (P = 0.025和P = 0.003,分别),但与基线没有差异.
- 1秒后兴奋能力的早期下降,随后稳定到接近基线水平.
结论:
- 在VIB诱导的幻觉中,皮质脊髓刺激性以特定时间的方式在与振动肌肉对抗的肌肉中进行调节.
- 观察到的兴奋能力的早期下降可能涉及脊柱机制,比如在幻觉完全被感知之前的相互抑制.
- 振动的神经调节效应依赖于时间,突出显示需要进一步研究底层的脊髓和皮质机制.
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