开放式和微创手术对前列腺手术患者术后伤口并发症的影响:元分析

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Jialiang Zhu¹, Ziwen Lu¹, Xianguo Cai¹

¹Department of Urology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, China.

International wound journal

|September 14, 2023

概括

与开放激进前列腺切除术 (ORP) 相比,前列腺癌的最小侵入性手术 (MIS) 减少了伤口感染和住院时间. 然而,MIS需要更长的操作时间,需要谨慎地解释结果.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
手术瘤学手术瘤学
基于证据的医学基于证据的医学.

背景情况:

根性前列腺切除术后的术后并发症显著影响患者的康复.
开放激进前列腺切除术 (ORP) 和微创手术 (MIS) 是常见的手术方法.
对ORP和MIS之间的并发症率和康复指标的比较分析对于治疗选择至关重要.

研究的目的:

分析和比较ORP和MIS在治疗术后并发症中的疗效.
评估外科手术对伤口并发症,手术时间和住院时间的影响.

主要方法:

一项从211个原始出版物中选择的六项研究的系统综述和元分析.
在四个主要数据库中进行的搜索:PubMed,EMBASE,科学网络和Cochrane图书馆.
主要结果:手术后伤口并发症的发生率;次要结果:手术时间和住院时间.

主要成果:

与开放激进前列腺切除术 (ORP) 相比,最小侵入性手术 (MIS) 显示伤口感染 (OR,0.61;p=0.01) 和出血 (MD,-293.09;p<0.0001) 的显著减少.
此外,MIS还导致住院时间缩短 (MD,-1.85天;p=0.03).
然而,MIS与显著更长的操作时间相关 (MD,51.45分钟;p<0.0001).

结论:

最少侵入性手术 (MIS) 与开放激进前列腺切除术 (ORP) 相比,在减少伤口并发症和前列腺癌治疗期间住院方面具有优势.
与MIS增加的操作时间值得考虑.
鉴于包含的研究中的有限数据和潜在偏差,研究结果应谨慎解释.

关键词:

微创手术是最少的侵入性手术.开放的激进前列腺切除术.伤口并发症伤口并发症

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