在非胸头症狗中监测食道pH值;一个参考
Tesheena R Nash1, Giselle L Hosgood1, Carla Appelgrein1
1The Animal Hospital at Murdoch University, Perth, Australia.
Veterinary surgery : VS
|September 14, 2023
概括
这项研究确定了住院狗中酸性胃食道逆流 (GER) 事件的上限. 这些参数有助于在接受食道pH监测的狗患者中识别过度的GER.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
背景情况:
- 酸性胃食道逆流 (GER) 是狗健康的一个问题.
- 确定GER的正常参数对于准确诊断至关重要.
- 之前的研究没有确定在麻醉下住院的狗的特定GER参数.
研究的目的:
- 定义描述非胸脑性狗中酸性胃食道逆流 (GER) 事件的参数.
- 为这些GER参数建立上限参考值.
- 帮助诊断住院犬患者的过度GER.
主要方法:
- 一项前性临床研究,涉及健康的客户拥有的狗接受选择性骨科手术.
- 狗接受了美沙,美德托米丁和阿尔法萨隆进行全静脉麻醉.
- 用Digitrapper探针进行食道双重pH监测,以记录GER事件 (pH <4.0).
主要成果:
- 包括35只狗,平均记录时间为21.1小时.
- 平均每小时的远端和近端GER事件分别为0.3和0.
- 平均累积的远端和近端食道酸暴露分别为0.2%和0%.
结论:
- 距离和近距离GER每小时的上限参考值分别为2.4和0.4.
- 累计远端和近端食道酸暴露的上限值分别为2.3%和0%.
- 超出这些极限的GER参数的狗可能具有过度的GER.
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