心力衰竭中的营养不良与保存的喷射分数
Omar Zainul1, Danny Perry2, Michael Pan3
1Weill Cornell Medical College, New York, New York, USA.
Journal of the American Geriatrics Society
|September 14, 2023
概括
营养不良影响42%的心力衰竭的成年人与保存的喷射分数 (HFpEF). 这种情况独立地增加了住院和六个月内死亡的风险.
科学领域:
- 老年医学 老年医学
- 心脏病学 心脏病学
- 营养科学 营养科学
背景情况:
- 营养不良是心力衰竭中潜在的老年问题,心力衰竭具有保存的射出分数 (HFpEF).
- 关于HFpEF患者的营养不良患病率和结果的数据有限.
研究的目的:
- 为了研究营养不良和 ambulatory HFpEF 患者的短期临床结果之间的关联.
- 确定营养不良是否预测了这一群体的发病率和死亡率.
主要方法:
- 分析了231名门诊HFpEF患者的队列.
- 营养不良被评估使用迷你营养评估简单表格 (MNA-SF) 评分≤11.
- 使用考克斯的比例危险模型评估了所有原因死亡率和住院的6个月复合终点.
主要成果:
- 营养不良的患病率为42% (97/231名患者).
- 营养不良与人体质量指数没有明显的相关性.
- 营养不良独立预测了6个月内所有原因死亡率和住院住院的复合结果 (HR1.94,p=0.01).
结论:
- 尽管肥胖率很高,但很大一部分HFpEF患者营养不良.
- 营养不良是门诊HFpEF中6个月不良结果的独立预测因素.
- 需要进一步的研究,以制定针对HFpEF营养不良的干预措施.
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