在单心室息治疗的患者中,机械心室置换
Conall T Morgan1,2, Devin Chetan1,2, Jaymie Varenbut3,4
1Division of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children.
概括
在单心室患者中,机械心室门置换具有高风险. 虽然它为那些保持心室功能的人提供了一些生存益处,但应该仔细考虑替代策略.
科学领域:
- 心脏病学 心脏病学
- 儿科心脏手术 儿科心脏手术
- 机械循环支持 机械循环支持
背景情况:
- 在单心室循环中,心室门 (AVV) 置换带来了相当大的外科手术挑战.
- 这些程序与高发病率和死亡率有关.
研究的目的:
- 评估功能单心室生理学患者机械AVV替代的结果.
- 评估无移植生存率和术后并发症.
主要方法:
- 1997年至2021年间连续16名接受机械AVV置换的患者的回顾性审查.
- 分析主要结局 (无移植生存) 和次要结局 (术后发病率).
主要成果:
- 手术死亡率为38%,无移植10年生存率为22%.
- 保持心室功能的患者表现出明显更高的无移植生存率.
- 主要并发症包括出血事件 (50%),膜血栓形成 (31%) 和完全的心脏阻塞 (19%).
结论:
- 在单心室患者中,机械AVV替代与重大风险有关.
- 这种手术对大约一半的心室功能保留的患者提供了生存优势.
- 在机械植入之前,替代治疗策略需要仔细考虑.
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