分析神经性肠道和膀功能障碍在宫脊髓炎解压手术后:一个前性队列研究
Ryo Kanematsu1, Junya Hanakita1, Tomoo Inoue1,2
1Department of Spinal Disorders Center, Fujieda Heisei Memorial Hospital, Fujieda, Japan.
Global spine journal
|September 14, 2023
概括
退行性宫髓病 (DCM) 影响超过40%的患者的肠道和膀功能. 宫减压手术为这些人中的很大一部分提供了症状改善.
科学领域:
- 神经外科 神经外科
- 脊髓疾病 脊髓疾病
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 胃肠病学 胃肠病学
背景情况:
- 退行性宫髓病 (DCM) 是一种渐进的脊髓疾病.
- 神经性肠道功能障碍和神经性膀是DCM中常见的并发症.
- 了解手术前的患病率和术后的结果对于患者管理至关重要.
研究的目的:
- 为了确定神经性肠道和膀功能障碍在DCM患者手术前的患病率.
- 评估宫减压后症状改善的程度和时间.
- 确定影响手术后症状恢复的因素.
主要方法:
- 75名DCM患者接受宫减压的前性观察性研究.
- 评估肠道 (便秘评分系统) 和膀 (国际前列腺症状评分) 功能障碍手术前和后 (1,3,6,12个月).
- 对患者人口统计,疾病特征和功能评分的分析 (日本骨科协会).
主要成果:
- 手术前排便和尿路功能障碍的患病率分别为41.3%和34.7%.
- 20-46%的患者在减压后12个月内观察到症状改善.
- 没有特定的患者因素与肠道或膀症状改善有显著的相关性,尽管下肢功能恢复显示出趋势.
结论:
- 神经性肠道和膀功能障碍在DCM患者中非常普遍.
- 宫减压手术可以导致这些功能对患者的一个子集的有意义的改善.
- 进一步的研究可能会阐明更好的功能恢复的预测因素.
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