在R2 *大脑地图中描述心脏引起的噪音
Quentin Raynaud1, Giulia Di Domenicantonio1, Jérôme Yerly2,3
1Laboratory for Research in Neuroimaging, Department for Clinical Neuroscience, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Magnetic resonance in medicine
|September 14, 2023
概括
心脏脉会在脑R2*图中引起显著的噪音,影响MRI数据. 本研究描述了这种噪声,并提出了一种新的采样策略,以减少其对R2*绘图的影响.
科学领域:
- 医疗成像医学成像
- 神经成像是一种神经成像.
- 生物物理学的生物物理.
背景情况:
- 心跳引入大脑中的噪音 R2*地图.
- 了解心脏引起的噪音对于准确的MRI数据采集至关重要.
- 由于这种噪声的未知特征,目前的缓解策略是有限的.
研究的目的:
- 为了描述心脏引起的大脑噪音R2*地图.
- 为了确定心脏脉对R2*映射的影响.
- 开发一种用于降低噪音的新型采样策略.
主要方法:
- 在12个心脏周期间隔中获得了多回声3DMRI数据.
- 使用脉冲氧计监测心脏周期.
- 分析了噪声振幅和k空间定位.
- 开发并测试了初步的降噪采样策略.
主要成果:
- 心脏脉会导致大脑下部区域 (大约3s-1R2*) 发生高达3s-1R2*的变化 35%的变化率).
- 在心脏周期的第一季度,噪声强度会降低.
- 50-60%的心脏噪声位于k空间中心附近 (k < 0.074 mm-1).
- 拟议的策略减少了R2*地图变异性,在脑干中减少了11%,在整个大脑中减少了6%.
结论:
- 在大脑R2*地图中,心脏引起的噪声是特征.
- 这些发现为设计有效的数据采集和缓解策略提供了基础.
- 开发的采样策略显示了在R2*映射中减少心脏噪声的潜力.
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