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IL-21,而不是IL-17A,加剧了小鼠初级胆道胆炎

Chun-Wen Chan1, Hung-Wen Chen1, Yu-Wen Wang1

  • 1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Clinical and experimental immunology
|September 14, 2023
PubMed
概括

干白素-21 (IL-21),而不是IL-17A,通过通过CD8+T细胞激活促进肝炎和纤维化来加剧原发性胆道胆道炎 (PBC). 这一发现为自身免疫性肝病提供了新的治疗点.

关键词:
Th17 这是一个很好的方法.自身免疫性疾病是一种自身免疫性疾病.这种药物是17A型中白素-17A.这种药物是17F型互白素.介质蛋白-21-21 介质蛋白组织居民记忆T细胞

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