Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Van der Waals Interactions01:24

Van der Waals Interactions

Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.
Frictional Force01:07

Frictional Force

When a body is in motion, it encounters resistance because the body interacts with its surroundings. This resistance is known as friction, a common yet complex force whose behavior is still not completely understood. Friction opposes relative motion between systems in contact, but also allows us to move. Friction arises in part due to the roughness of surfaces in contact. For one object to move along a surface, it must rise to where the peaks of the surface can skip along the bottom of the...
Contact Angle01:13

Contact Angle

When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive force...
Impact01:30

Impact

Impact occurs when two bodies collide, leading to the application of impulsive forces between them. Analyzing impact mechanics involves considering two colliding particles moving along a line known as the line of impact, which passes through their centers and is perpendicular to the contact plane.
When particles with different initial velocities collide, they induce deformation by applying equal and opposite impulses. At the point of maximum deformation, the particles move together with...
Surface Tension01:24

Surface Tension

Surface tension is defined as the force per unit length (γ) acting along the surface of a liquid. It arises due to strong intermolecular forces of attraction. A molecule located inside the bulk of the liquid is surrounded by other molecules and experiences equal forces in all directions. However, a molecule at the surface experiences unbalanced forces because there are more neighboring molecules below than above. This creates a net inward force that pulls surface molecules toward the interior,...
Microbial Interactions: Mutualism01:25

Microbial Interactions: Mutualism

Mutualism is a symbiotic interaction in which all participating organisms benefit. These relationships can be obligate or facultative and are fundamental to ecosystem functions across diverse biological systems.Plant–Fungi MutualismOne well-known example is the association between plant roots and mycorrhizal fungi, such as Rhizophagus species. The fungal hyphae penetrate the root hairs and the epidermis, forming an extensive hyphal network that establishes a symbiotic association. Through this...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A P2RY12 Deficiency Results in Sex-specific Cellular Perturbations and Sexually Dimorphic Behavioral Anomalies.

Research square·2024
Same author

Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior.

Molecular psychiatry·2023
Same author

Microglia states and nomenclature: A field at its crossroads.

Neuron·2022
Same author

Differential Expression of CD49a and CD49b Determines Localization and Function of Tumor-Infiltrating CD8<sup>+</sup> T Cells.

Cancer immunology research·2021
Same author

Astrocyte development: A Guide for the Perplexed.

Glia·2015
Same author

Imaging microglia in brain slices and slice cultures.

Cold Spring Harbor protocols·2013
Same journal

A native sulfur deposit in Gale crater, Mars.

Science (New York, N.Y.)·2026
Same journal

Coordinated demise of harmful algal blooms.

Science (New York, N.Y.)·2026
Same journal

Genetic effects put into context.

Science (New York, N.Y.)·2026
Same journal

Bacteria share proteins to survive antibiotics.

Science (New York, N.Y.)·2026
Same journal

Impacts shaped Earth's first continents.

Science (New York, N.Y.)·2026
Same journal

Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

Science (New York, N.Y.)·2026
查看所有相关文章

相关实验视频

Updated: May 7, 2026

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility
07:54

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility

Published on: April 13, 2017

9.8K

定义微质突触相互作用

Ukpong Eyo1, Anna Victoria Molofsky2

  • 1Center for Brain Immunology and Glia, Neuroscience Department, University of Virginia School of Medicine, Charlottesville, VA, USA.

Science (New York, N.Y.)
|September 14, 2023
PubMed
概括
此摘要是机器生成的。

脑中的免疫细胞微细胞不仅仅是修剪突触. 这项研究探讨了它们在大脑健康和疾病中的不同功能.

更多相关视频

Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology
07:41

Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology

Published on: May 31, 2024

1.2K
Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions
08:47

Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions

Published on: July 26, 2024

2.2K

相关实验视频

Last Updated: May 7, 2026

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility
07:54

Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility

Published on: April 13, 2017

9.8K
Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology
07:41

Author Spotlight: Advancing Understanding Through Technological Innovations in Psychoneuroimmunology

Published on: May 31, 2024

1.2K
Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions
08:47

Author Spotlight: In Vitro Co-Culture Model for Studying Microglia-Neuronal Interactions in Disease Conditions

Published on: July 26, 2024

2.2K

科学领域:

  • 神经科学
  • 免疫学
  • 细胞生物学

背景情况:

  • 微质细胞是位于中枢神经系统的主要免疫细胞.
  • 传统上,它们在发育和可塑性过程中的突触修剪作用被强调.

研究的目的:

  • 研究大脑内巨细胞 (微细胞) 在已知的突触修剪功能之外的多方面的作用.
  • 突出微质对中枢神经系统稳定性和病理学的更广泛影响.

主要方法:

  • 对微质功能现有文献的审查.
  • 来自各种神经模型的实验数据的分析.
  • 对不同大脑状态中的微质行为进行比较研究.

主要成果:

  • 微细胞参与免疫监测,碎片清除和神经营养因子释放.
  • 它们的失调与神经炎症和神经退行性疾病有关.
  • 微细胞积极调节神经元活动和网络功能.

结论:

  • 微质细胞具有非常重要的维护和修复功能.
  • 了解这些不同角色对于开发神经系统疾病的新疗法至关重要.