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Updated: Apr 7, 2026

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选择性蛋白质降解通过分裂和混合脂质体蛋白质分解以向奇美拉方法

Chunli Song1, Zijun Jiao2,3, Zhanfeng Hou1

  • 1State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.

Journal of the American Chemical Society
|September 14, 2023
PubMed
概括

这项研究引入了一种基于脂质体的分离和混合蛋白质溶解向基因组 (PROTAC) 系统. 这种新型LipoSM- PROTAC在较低度下显示出增强的瘤向和蛋白质降解效果.

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