腹淋巴瘤与腹肉类粉症结合
Hiroki Tashiro1, Koichiro Takahashi1, Natsuko Komiya1
1Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University Hospital, Saga, Japan.
Respiratory investigation
|September 14, 2023
概括
沙丘病可以呈现为多叶膜溢出. 在这种情况下,额头膜中的异常细胞导致了恶性B细胞淋巴瘤的诊断,这与沙尔科毒症的发现不同.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 沙尔科病是一个炎症性疾病,可以影响膜.
- 胸腔溢出是已知的,虽然不常见的,萨尔科伊多सिस的表现.
- 在膜中区分瘤过程与肉类发病症可能是具有挑战性的.
研究的目的:
- 报告一种罕见的同时存在的肉性瘤和多发性恶性B细胞淋巴瘤的病例.
- 强调彻底的病理检查的重要性 胸腔异常的病理检查.
- 讨论区分肺部沙尔科毒症和淋巴瘤的诊断挑战.
主要方法:
- 一个病人的病例报告,患有巨大的肺溢液.
- 诊断工作包括胸部计算机断层扫描 (CT) 和胸腔镜.
- 胸腔活检的组织病理学检查与免疫组织化学.
主要成果:
- 患者呈现了大量的左侧膜溢出,发现结果与肉类症一致 (状淋巴结核病,肺结节).
- 胸腔镜检查显示了内脏膜上的结节,被证实为上皮状颗粒瘤.
- 意想不到的是,表皮膜显示出异常细胞对白细胞常见抗原,CD20和CD79a呈阳性,表明恶性B细胞淋巴瘤.
结论:
- 这一案例表明了罕见的萨尔科毒症和原发性腹B细胞淋巴瘤共存的例子.
- 免疫组织化学标志物对于区分淋巴瘤与膜中的颗粒状炎症至关重要.
- 恶性B细胞淋巴瘤应考虑在膜异常的差异性诊断中,即使在已知的肉类瘤患者中也是如此.
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