肠道微生物群:间歇性禁食和瘤之间的桥梁
Jing Liu1, Nan Shao1, Hui Qiu1
1Special Key Laboratory of Gene Detection &Therapy of Guizhou Province, Zunyi Medical University, Zunyi, Guizhou 563000, China; Department of Immunology, Zunyi Medical University, Zunyi, Guizhou 563000, China.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|September 14, 2023
概括
间歇性禁食 (IF) 影响肠道微生物群,影响瘤生长和免疫反应. 本综述探讨了IF和肠道微生物如何为癌症干预提供新的策略.
科学领域:
- 微生物学 微生物学
- 在瘤学瘤学.
- 营养科学 营养科学
背景情况:
- 肠道微生物群和代谢物对肠道健康,免疫力和炎症调节至关重要.
- 肠道微生物群的组成与癌症的发展和治疗疗效有关.
- 间歇性禁食 (IF) 显示出改善新陈代谢,寿命和疾病进展的潜力,包括癌症.
研究的目的:
- 审查肠道微生物群在各种瘤中的作用.
- 要总结间歇性禁食 (IF) 对肠道微生物群的影响.
- 讨论IF和肠道微生物群作为联合抗瘤战略的潜力.
主要方法:
- 文献综述综合了关于肠道微生物群,IF和癌症的当前研究.
- 分析IF影响瘤细胞代谢和免疫反应的机制.
- 检查IF如何改变肠道微生物的组成和功能.
主要成果:
- IF影响瘤细胞的能量代谢,抑制生长,并增强抗瘤免疫力.
- IF显著改变了肠道微生物群的组成和代谢活动.
- 在IF,肠道微生物群和瘤抑制作用之间存在复杂的相互作用.
结论:
- 间歇性禁食 (IF) 通过其对肠道微生物群的影响,显示出其作为癌症干预策略的前景.
- 需要进一步研究以阐明具体机制并优化临床应用.
- 将IF与肠道微生物群的调节结合起来,可能为癌症提供新的治疗方法.
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