在老年人中,左心房应变和发生性心房
Carlo Mannina1, Kazato Ito2, Zhezhen Jin3
1Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
The American journal of cardiology
|September 14, 2023
概括
减少左心房应变和应变率可以预测老年人新发性心房动. 这些心声回声测量可以改善心房的风险分层,即使在左心房大小正常的个体中也是如此.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 老年病的医生 老年病的医生
背景情况:
- 心房动 (AF) 在老年人中很常见,与左心房 (LA) 功能障碍有关.
- 亚临床LA疾病可以通过LA菌株 (LAε) 和LA菌株速率 (LASR) 来检测.
- 在没有先前的AF或中风的老年人中预测新发性AF至关重要.
研究的目的:
- 调查是否降低LAε和LASR可以预测老年人新发性AF.
- 评估LAε和LASR与事件AF的关联,独立于LA大小和LV功能.
主要方法:
- 在824名参与者 (平均年龄为71.1岁) 中,Speckle追踪回声心脏学评估了LAε和LASR.
- 测量包括阳性纵向LAε,心室静脉缩期间的LASR,早期心房静脉缩和LA收缩.
- 因果特异性危险回归评估了在平均10.9年的随访期间与事件AF的关联.
主要成果:
- 在随访期间,105名参与者 (12.7%) 发生了新发性AF.
- 在患有新发性AF的参与者中观察到较低的基线LAε和LASR (p <0.01).
- 在LA收缩期间减少的阳性纵向LAε和LASR独立预测新发AF.
结论:
- 减少的正纵向LAε和LASR预测了老年人新发的AF.
- 这些心声回声学参数可能会增加AF风险分层,无论LA大小如何.
- 拉动脉应变和拉动脉应变率为亚临床拉动脉功能障碍和AF风险提供了宝贵的见解.
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