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Updated: Jul 16, 2025

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
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High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model

Published on: August 16, 2019

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AKT抑制产生强大的多功能临床级AUTO1 CAR T细胞,增强功能和生存能力

Vedika Mehra1, Giulia Agliardi1,2, Juliana Dias Alves Pinto1,2

  • 1Research Department of Haematology, University College London, London, UK.

Journal for immunotherapy of cancer
|September 14, 2023
PubMed
概括

一种AKT抑制剂 (VIII) 通过丰富Tscm/Tcm细胞来改善AUTO1 CAR-T细胞治疗成人淋巴细胞白血病. 这增强了CAR-T细胞的扩张,持久性和抗瘤活性,可能克服CD19+复发.

关键词:
细胞因子 (cytokines) 是一种细胞因子.免疫治疗是一种免疫疗法.的T-淋巴细胞.翻译医学研究 翻译医学研究

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