在面外伤手术中手术部位感染 - 单剂量与长期抗生素预防
Jan Gaessler1, Dominic Morocutti2, Markus Merkl1
1Division of Oral and Maxillofacial Surgery, Department of Dental Medicine and Oral Health, Medical University of Graz, Auenbruggerplatz 5, 8010, Graz, Austria.
概括
对比单剂量与面部骨折手术的长期抗生素预防,在手术部位感染率或严重程度上没有显著差异. 这表明较短的抗生素持续时间可能足以通过内部固定程序进行开放的减少.
科学领域:
- 口腔和牙面部外科手术
- 传染性疾病 传染性疾病
- 创伤外科 手术 创伤外科
背景情况:
- 面部骨折的内部固定 (ORIF) 的开放性减少通常因手术部位感染 (SSI) 而复杂化.
- 术后抗生素预防是ORIF的标准做法,以减轻感染风险.
研究的目的:
- 在接受ORIF治疗面部骨折的患者中,比较单剂量抗生素预防 (SDAP) 和长期抗生素预防 (PAP) 之间的SSI发生率和严重程度.
主要方法:
- 对122名接受面部骨折ORIF治疗的患者进行了回顾性分析.
- 患者被分为两个组:SDAP (单次术后剂量) 和PAP (5天疗程).
- 两个抗生素预防组之间的SSI率和严重程度的比较.
主要成果:
- 在SDAP组的9名患者和PAP组的15名患者患上SSI;发生率没有统计学上显著的差异 (p=0.218).
- 在SSI的严重程度上,SDAP和PAP组之间也没有显著差异 (p=0.982).
结论:
- 单剂量或长期抗生素预防都没有在预防或减少面部骨折ORIF后SSI的严重性方面显示出显著的优势.
- 研究结果表明,目前的长期抗生素预防方案可能不会为这种患者群体提供比单剂量疗法更多的好处.
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