相关实验视频

Updated: Jul 16, 2025

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry
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SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry

Published on: January 6, 2017

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鉴定了一种具有不同的C端,但完整的二元化性质的新型索尔辛异型

Supriya Tanwar1, Faizan Abul Qais2, Farheen Naaz1

  • 1Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India.

Scientific reports
|September 14, 2023
PubMed
概括

研究人员发现了一种新的小鼠蛋白质异型,Sorcin-N (Sri-N),其C端域不同. 这种新型异构体与以前已知的Sorcin (Sri) 蛋白相比,对化疗药物具有增强的结合亲和力.

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相关概念视频

Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
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