能量平衡转变对骨质和强度的影响
Ian J Wallace1, Christopher Toya2, Mario Antonio Peña Muñoz3
1Department of Anthropology, University of New Mexico, Albuquerque, NM, 87131, USA. iwallace@unm.edu.
Scientific reports
|September 14, 2023
概括
能量平衡的转变,以增加卡路里摄入量和减少活动为标志,导致新墨西哥州土著人民的骨强度下降和骨折风险增加. 这凸显了全球对骨脆弱性的日益关注.
科学领域:
- 人类生物学 人类生物学
- 骨的健康 骨的健康
- 人类学是人类学.
背景情况:
- 慢性正能量平衡,称为能量平衡过渡,是由饮食和活动变化驱动的全球健康问题.
- 这种转变与肥胖率的上升和潜在的负面健康结果有关.
- 骨健康是整体健康的关键组成部分,受到生活方式因素的影响.
研究的目的:
- 研究能量平衡转变对骨质和强度的影响.
- 分析新墨西哥州土著人民在转型之前和之后骨质特性变化的情况.
- 了解在经历这种转变的人群中对骨折风险的影响.
主要方法:
- 骨质量和强度数据的比较分析.
- 专注于新墨西哥州的土著人民作为一个独特的研究人口.
- 对活在能量平衡转变之前和之后的个体的数据进行了检查.
主要成果:
- 在能量平衡过渡后,腿部骨强度显著下降.
- 矛盾的是,骨质似乎有所增加.
- 个人现在表现出较弱的骨头,承受更重的负载,增加骨折的风险.
结论:
- 能量平衡的转变会对骨强度产生负面影响,增加骨脆弱性.
- 肥胖会加剧受影响人群骨折的风险.
- 研究结果提供了关于骨脆弱性和骨折风险的全球趋势的见解.
相关概念视频
Bone Disorders
3.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.6K
Bone Remodeling
38.4K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.4K
Energy Balance
446
The human body gets energy from the three macronutrients: carbohydrates, proteins, and fats. Energy is released when the chemical bonds in the organic compounds present in the food are broken down. The energy content of food is measured in kilocalories (kcal), defined as the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius. This value is determined by measuring the temperature change of the water surrounding a calorimeter after the complete...
446
Hormones and Bone Tissue
2.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K
Essential Minerals for Bone Health
4.1K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
4.1K
The Functions of the Skeletal System
3.9K
The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
3.9K


