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Updated: Jul 16, 2025

Biophysical Assays to Probe the Mechanical Properties of the Interphase Cell Nucleus: Substrate Strain Application and Microneedle Manipulation
16:27

Biophysical Assays to Probe the Mechanical Properties of the Interphase Cell Nucleus: Substrate Strain Application and Microneedle Manipulation

Published on: September 14, 2011

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氨酸 - 氨酸链接保护核免受机械变形和信号传输

Zanetta Kechagia1, Pablo Sáez2,3, Manuel Gómez-González4

  • 1Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. jkechagia@ibecbarcelona.eu.

Nature materials
|September 14, 2023
PubMed
概括

拉米宁保护乳腺上皮细胞核免受机械应力,阻碍它们对组织刚性的反应. 阻断整合素β4可以逆转这种效应,揭示了组织机械敏感性调节的新机制.

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