维生素E和糖尿病足部
Nikolaos D Karakousis1, Elisavet E Pyrgioti2, Petros N Georgakopoulos3
1Second Department of Internal Medicine, Diabetes Centre-Diabetic Foot Clinic, Democritus University of Thrace, Alexandroupolis, Greece.
Current diabetes reviews
|September 15, 2023
概括
糖尿病足 (DFU) 的维生素E水平可能较低,但证据是混合的. 补充可能有助于预防和治愈糖尿病患者的DFU,这需要进一步的研究.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 伤口治愈研究研究 伤口治愈研究
背景情况:
- 糖尿病足 (DFU) 是糖尿病 (DM) 的一个重要并发症.
- 维生素E是一种强大的抗氧化剂,在细胞健康和免疫功能中起作用.
- 在各种慢性疾病 (包括糖尿病) 中,建议改变维生素E水平.
研究的目的:
- 审查有关DFU患者维生素E状况的当前文献.
- 评估维生素E在治疗糖尿病及其并发症,特别是糖尿病发育不良症方面的潜在治疗作用.
- 识别知识上的差距,并建议未来的研究方向.
主要方法:
- 现有研究的叙述性小回顾.
- 对DFU患者维生素E水平数据的分析.
- 关于在DM和DFU管理中补充维生素E的证据综合.
主要成果:
- 患有DFU的受试者的维生素E水平显示不一致的发现,一些研究表明减少.
- 维生素E的使用可以通过延迟并发症,包括DFU,使DM患者受益.
- 初步证据表明,维生素E可能会促进现有的DFU的愈合.
结论:
- 由于不一致的发现,维生素E在DFU病变发生中的作用需要进一步阐明.
- 维生素E补充剂在糖尿病患者的DFU预防和治疗方面表现有前途.
- 维生素E对DFU管理的成本效益和最终有效性需要进行额外的严格研究.
相关概念视频
Peripheral Artery Disease IV: Nursing Management
12
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
12
Venous Thrombosis III: Interprofessional Care
10
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
10
Pathophysiology of Diabetes
980
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
980
Diabetes: Management and Pharmacotherapy
309
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
309
Clinical Applications of Epidermal Stem Cells
2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
Peripheral Artery Disease III: Interprofessional Care
11
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
11


