2023年中国脂质管理指南
Jian-Jun Li1, Shui-Ping Zhao2, Dong Zhao3
1National Center for Cardiovascular Diseases, FuWai Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Frontiers in pharmacology
|September 15, 2023
概括
新的中国脂质管理指南强调控制低密度脂蛋白胆固醇 (LDL-C),以预防动脉样硬化心血管疾病 (ASCVD). 他们建议对高风险人群使用他类药物和改变生活方式,以及其他药物.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 临床实践指南 临床实践指南
背景情况:
- 动脉样性心血管疾病 (ASCVD) 是中国的主要死亡原因.
- 低密度脂蛋白胆固醇 (LDL-C) 的升高是ASCVD的重要危险因素.
- 越来越多的ASCVD负担需要更新的脂质管理策略.
研究的目的:
- 修订和更新中国脂质管理指南.
- 为控制LDL-C和预防ASCVD提供基于证据的建议.
- 针对基于个体ASCVD风险的不同目标脂质水平.
主要方法:
- 专家委员会对现有的失脂症指南进行调整.
- 纳入最近关于血脂的全球研究.
- 确定目标LDL-C水平的风险分层.
主要成果:
- 低密度脂蛋白胆固醇 (LDL-C) 仍然是脂质控制的主要目标.
- 心血管疾病 (CVD) 风险分层被用来设定LDL-C目标.
- 最初的治疗包括中等强度的他类药物和生活方式的改变.
- 根据需要,建议使用额外的疗法,如PCSK9抑制剂.
结论:
- 新指南为所有年龄组提供了全面的脂质管理策略.
- 他们的目标是改善ASCVD预防和治疗的临床实践.
- 鉴于脂质研究的进步和ASCVD负担,更新的指南至关重要.
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