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Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
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在基中准殖民地刺激因子-1受体:划出癌症免疫治疗的界限

Zahra Azhar1, Richard P Grose1, Afsheen Raza2

  • 1Centre of Tumour Biology, Barts Cancer Institute, Queen Mary University of London, EC1M 6BQ London, UK.

Exploration of targeted anti-tumor therapy
|September 15, 2023
PubMed
概括

针对殖民地刺激因子-1受体 (CSF1R) 的小分子抑制剂被分析为癌症疗法. 由于它们的结构稳定性和结合亲和力,DCC-3014和ARRY-382显示出显著的潜力.

关键词:
癌症药物开发 癌症药物开发计算建模计算建模药物耐药性 耐药性 药物耐药性领先优化优化 领先优化分子对接的分子对接.目标识别 目标识别有针对性的癌症治疗.铁氨基激酶抑制剂 铁氨基激酶抑制剂

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