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同步黑色素瘤:定义,预后和影响. 一个全面的文学评论
Ajaipal S Kang1, Rahul Rajput2, Genelia Kang3
1From the Department of Surgery, UPMC Hamot, Erie, Pa.
Plastic and reconstructive surgery. Global open
|September 15, 2023
概括
同步黑色素瘤 (SMs) 被定义为在1个月内诊断出第二次原发性黑色素瘤,占多发性原发性黑色素瘤 (MPMs) 的近三分之一. 这些MS病例的预后并不比单个黑色素瘤更糟.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 医学研究 医学研究
背景情况:
- 多重原发性黑色素瘤 (MPMs) 已被记录,但同步性黑色素瘤 (SMs) 尚未得到研究.
- 关于中小企业的定义和特征存在缺乏共识.
研究的目的:
- 系统地审查文献并描述同步黑色素瘤 (SMs).
- 澄清SMs的定义,发病率和预后.
- 为SM诊断和管理提供基于证据的建议.
主要方法:
- 1972年至2023年的英语文学综合系统审查.
- 纳入标准侧重于病例系列和病例报告,详细介绍同步黑色素瘤.
- 数据提取和合成以确定定义,发病率和患者特征的趋势.
主要成果:
- 分析了18个病例系列和6个病例报告,共计1083名MS患者.
- 在12项研究中,MS被定义为1个月内诊断的第二次原发性黑色素瘤.
- 黑色素瘤占MPM病例的31.3% (占所有黑色素瘤患者的2.9%),其趋势是年龄较大,男性性别较高,以及更高的身体解剖学一致性.
结论:
- 建议将同步黑色素瘤 (SM) 定义为在1个月内诊断的第二次原发性黑色素瘤.
- 多发性初级黑色素瘤约占多发性初级黑色素瘤 (MPMs) 的三分之一,并且似乎不会导致更糟糕的预后.
- 高龄和男性性别可能是MS的风险因素;建议患者接受教育并定期进行皮肤评估.
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