在患有阻塞性冠状动脉疾病的患者中,EAS指数的预后值
Bo Kong1, Lemei Hu2,3, Quanjun Liu1,2
1Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Quantitative imaging in medicine and surgery
|September 15, 2023
概括
EAS指数独立预测冠状动脉疾病 (CAD) 患者的主要不良心血管事件 (MACE). 这种新的工具增强了风险分层,特别是在左心室喷射分数 (LVEF) 保存的患者中.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 风险分层是风险的分层.
背景情况:
- EAS指数是一种新型参数,通过组织多普勒成像 (TDI) 进行评估.
- 它被提议作为冠状动脉疾病 (CAD) 患者风险分层的辅助工具,补充左心室喷射分数 (LVEF).
研究的目的:
- 评估EAS指数对阻塞性CAD患者心血管结果的预测值.
- 评估它在不同水平的心脏缩功能中的实用性.
主要方法:
- 一项前性队列研究包括477名患有阻塞性CAD的患者.
- 使用TDI测量了EAS指数 (e'/(a' × s')) 的值.
- 主要不良心血管事件 (MACE) 记录了6个月,复合事件的长期随访. 进行了生存和考克斯回归分析.
主要成果:
- 经过多变量调整后,EAS指数的升高与MACE的更高发病率显著相关 (HR:1.81,95% CI:1.15-2.85).
- 这种关联在LVEF≥50% (P<0.05) 的患者中是显著的.
- 101 MACE 和 139 个复合事件发生在 25.9 个月的中位随访期间.
结论:
- EAS指数是阻塞性CAD患者中MACE的独立预测指标.
- 它可以作为CAD患者风险分层的一个有价值的工具.
- 将EAS指数纳入预测模型可以提高其有效性.
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