冠状动脉炎症与冠状动脉硬化负担之间是否存在关联?
Mengyuan Jing1,2,3,4, Huaze Xi1,2,3,4, Hao Zhu1,2,3,4
1Department of Radiology, Lanzhou University Second Hospital, Lanzhou, China.
Quantitative imaging in medicine and surgery
|September 15, 2023
概括
冠状动脉炎症,通过冠状周脂肪组织 (PCAT) 衰减来评估,与冠状动脉样硬化负担 (CAC评分) 没有直接相关. 然而,炎症在冠状动脉疾病患者中最高,CAC得分为0.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 生物医学工程 生物医学工程
背景情况:
- 评估心脏不良事件风险包括评估冠状动脉炎症和动脉样硬化负担.
- 这两个因素之间的相关性仍然不清楚.
- 这项研究调查了冠状动脉炎症和动脉样硬化负担之间的关系.
研究的目的:
- 探索冠状动脉炎症与冠状动脉硬化负担之间的潜在关系.
- 为了确定冠状动脉炎症是否与冠状动脉硬化负担相关.
主要方法:
- 346名患者接受了CT扫描,以评估周冠状动脉脂肪组织 (PCAT) 衰减和Agatston冠状动脉 (CAC) 评分.
- PCAT减弱测量了冠状动脉炎症,而CAC得分评估了动脉样硬化负担.
- 患者根据CAC得分 (0,≥10,≥100,≥400) 和CAD存在情况进行分组.
主要成果:
- 冠状动脉疾病 (CAD) 患者的PCAT衰减明显高于非CAD患者.
- 与CAC 0的非CAD患者和CAC > 0.的CAD患者相比,CAC分数为0的CAD患者显示出较高的PCAT衰减.
- 不同CAC得分之间没有发现PCAT减弱的显著差异,但在CAC0.0的CAD患者中,它是最高的.
结论:
- 冠状动脉炎症和动脉样硬化负担之间没有明显的直接关系.
- 冠状动脉炎症在CAD患者中最明显,其CAC得分为0.
- CAC评分没有表明与冠状动脉炎症的关联.
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