女性循环重金属度与堕胎之间的关联:系统性审查和元分析
Meiqi Ren1, Liantong Wang1, Liqin Wen2
1Center for Reproductive Medicine, Department of Obstetrics and Gynaecology, NanFang Hospital, Southern Medical University, Guangzhou, China.
Frontiers in endocrinology
|September 15, 2023
概括
暴露于重金属,包括和,以及缺和铜,与自发流产和重复流产有关. 内分泌功能障碍可能在这些关联中发挥作用.
科学领域:
- 环境健康 环境健康
- 生殖毒理学 生殖毒理学
- 生物化学 生物化学
背景情况:
- 自发流产 (SA) 和重复流产 (RPL) 是重要的生殖健康问题.
- 重金属暴露和营养不足在怀孕结果中的作用需要进一步调查.
结论:
- 血液中的重金属含量,特别是Zn和Cu的缺乏以及Pb和Cd的暴露,与堕胎有关.
- 潜在的机制涉及内分泌功能障碍,包括胰岛素抵抗,维生素D不足和荷尔蒙失衡.
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